The Enzyme Database

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Accepted name: 7-methylguanosine nucleotidase
Reaction: (1) N7-methyl-GMP + H2O = N7-methyl-guanosine + phosphate
(2) CMP + H2O = cytidine + phosphate
Other name(s): cytosolic nucleotidase III-like; cNIII-like; N7-methylguanylate 5′-phosphatase
Systematic name: N7-methyl-GMP phosphohydrolase
Comments: The enzyme also has low activity with N7-methyl-GDP, producing N7-methyl-GMP. Does not accept AMP or GMP, and has low activity with UMP.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB
1.  Buschmann, J., Moritz, B., Jeske, M., Lilie, H., Schierhorn, A. and Wahle, E. Identification of Drosophila and human 7-methyl GMP-specific nucleotidases. J. Biol. Chem. 288 (2013) 2441–2451. [DOI] [PMID: 23223233]
[EC created 2013]

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