| EC |
3.1.3.88 |
| Accepted name: |
5′′-phosphoribostamycin phosphatase |
| Reaction: |
5′′-phosphoribostamycin + H2O = ribostamycin + phosphate |
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For diagram of neamine and ribostamycin biosynthesis, click here |
| Other name(s): |
btrP (gene name); neoI (gene name) |
| Systematic name: |
5′′-phosphoribostamycin phosphohydrolase |
| Comments: |
Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including ribostamycin, neomycin and butirosin. No metal is required for activity. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Kudo, F., Fujii, T., Kinoshita, S. and Eguchi, T. Unique O-ribosylation in the biosynthesis of butirosin. Bioorg. Med. Chem. 15 (2007) 4360–4368. [DOI] [PMID: 17482823] |
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| [EC 3.1.3.88 created 2012] |
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