The Enzyme Database

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Accepted name: ribonuclease P
Reaction: Endonucleolytic cleavage of RNA, removing 5′-extranucleotides from tRNA precursor
Other name(s): RNase P
Comments: An RNA-containing enzyme, essential for tRNA processing; generates 5′-termini or mature tRNA molecules.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB
1.  Bikoff, E.K. and Gefter, M.L. In vitro synthesis of transfer RNA. I. Purification of required components. J. Biol. Chem. 250 (1975) 6240–6247. [PMID: 1099089]
2.  Bikoff, E.K., La Rue, B.F. and Gefter, M.L. In vitro synthesis of transfer RNA. II. Identification of required enzymatic activities. J. Biol. Chem. 250 (1975) 6248–6255. [PMID: 1099090]
3.  Robertson, H.D., Altman, S. and Smith, J.D. Purification and properties of a specific Escherichia coli ribonuclease which cleaves a tyrosine transfer ribonucleic acid presursor. J. Biol. Chem. 247 (1972) 5243–5251. [PMID: 4560501]
[EC created 1978, modified 1982]

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