| EC |
3.1.25.1 |
| Accepted name: |
deoxyribonuclease (pyrimidine dimer) |
| Reaction: |
Endonucleolytic cleavage near pyrimidine dimers to products with 5′-phosphate |
| Other name(s): |
endodeoxyribonuclease (pyrimidine dimer); endodeoxyribonuclease (pyrimidine dimer); bacteriophage T4 endodeoxyribonuclease V; T4 endonuclease V |
| Comments: |
Acts on a damaged strand, 5′ from the damaged site. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 66143-22-4 |
| References: |
| 1. |
Braun, A.G., Radman, M. and Grossman, L. Enzymic repair of DNA: sites of hydrolysis by the Escherichia coli endonuclease specific for pyrimidine dimers (corendonuclease II). Biochemistry 15 (1976) 4116–4120. [PMID: 786366] |
| 2. |
Riazuddin, S. and Grossman, L. Micrococcus luteus correndonucleases. II. Mechanism of action of two endonucleases specific for DNA containing pyrimidine dimers. J. Biol. Chem. 252 (1977) 6287–6293. [PMID: 330526] |
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| [EC 3.1.25.1 created 1978] |
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