| EC |
3.1.2.12 |
| Accepted name: |
S-formylglutathione hydrolase |
| Reaction: |
S-formylglutathione + H2O = glutathione + formate |
| Systematic name: |
S-formylglutathione hydrolase |
| Comments: |
Also hydrolyses S-acetylglutathione, but more slowly. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 83380-83-0 |
| References: |
| 1. |
Uotila, L. Preparation and assay of glutathione thiol esters. Survey of human liver glutathione thiol esterases. Biochemistry 12 (1973) 3938–3943. [PMID: 4200890] |
| 2. |
Uotila, L. and Koivusalo, M. Purification and properties of S-formylglutathione hydrolase from human liver. J. Biol. Chem. 249 (1974) 7664–7672. [PMID: 4436331] |
| 3. |
Harms, N., Ras, J., Reijnders, W.N., van Spanning, R.J. and Stouthamer, A.H. S-Formylglutathione hydrolase of Paracoccus denitrificans is homologous to human esterase D: a universal pathway for formaldehyde detoxification? J. Bacteriol. 178 (1996) 6296–6299. [DOI] [PMID: 8892832] |
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| [EC 3.1.2.12 created 1978] |
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