| EC |
2.8.2.11 |
| Accepted name: |
galactosylceramide sulfotransferase |
| Reaction: |
3′-phosphoadenylyl sulfate + a galactosylceramide = adenosine 3′,5′-bisphosphate + a galactosylceramidesulfate |
| Glossary: |
3′-phosphoadenylyl sulfate = PAPS |
| Other name(s): |
GSase; 3′-phosphoadenosine-5′-phosphosulfate-cerebroside sulfotransferase; galactocerebroside sulfotransferase; galactolipid sulfotransferase; glycolipid sulfotransferase; glycosphingolipid sulfotransferase; 3′-phosphoadenylyl-sulfate:galactosylceramide 3′-sulfotransferase |
| Systematic name: |
3′-phosphoadenylyl-sulfate:galactosylceramide 3′-sulfonotransferase |
| Comments: |
Also acts on lactosylceramide. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 9081-06-5 |
| References: |
| 1. |
McKhann, G.M., Levy, R. and Ho, W. Metabolism of sulfatides. I. The effect of galactocerebrosides on the synthesis of sulfatides. Biochem. Biophys. Res. Commun. 20 (1965) 109–113. [DOI] [PMID: 5850675] |
| 2. |
Sakakibara, N., Gasa, S., Kamio, K., Makita, A. and Koyanagi, T. Association of elevated sulfatides and sulfotransferase activities with human renal cell carcinoma. Cancer Res. 49 (1989) 335–339. [PMID: 2562926] |
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| [EC 2.8.2.11 created 1972, modified 1976] |
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