The Enzyme Database

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Accepted name: polyribonucleotide nucleotidyltransferase
Reaction: RNAn+1 + phosphate = RNAn + a nucleoside diphosphate
Other name(s): polynucleotide phosphorylase; PNPase (ambiguous); nucleoside diphosphate:polynucleotidyl transferase; polyribonucleotide phosphorylase
Systematic name: polyribonucleotide:phosphate nucleotidyltransferase
Comments: ADP, IDP, GDP, UDP and CDP can act as donors.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB, CAS registry number: 9014-12-4
1.  Hakim, A.A. Synthetic activity of polynucleotide phosphorylase from sperm. Nature 183 (1959) 334. [PMID: 13632712]
2.  Littauer, U.Z. and Kornberg, A. Reversible synthesis of polyribonucleotides with an enzyme from Escherichia coli. J. Biol. Chem. 226 (1957) 1077–1092. [PMID: 13438894]
3.  Ochoa, S. and Mii, S. Enzymatic synthesis of polynucleotides. IV. Purification and properties of polynucleotide phosphorylase from Azotobacter vinelandii. J. Biol. Chem. 236 (1961) 3303–3311. [PMID: 14481058]
[EC created 1961]

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