| EC |
2.7.1.49 |
| Accepted name: |
hydroxymethylpyrimidine kinase |
| Reaction: |
ATP + 4-amino-5-hydroxymethyl-2-methylpyrimidine = ADP + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine |
| Other name(s): |
hydroxymethylpyrimidine kinase (phosphorylating) |
| Systematic name: |
ATP:4-amino-5-hydroxymethyl-2-methylpyrimidine 5-phosphotransferase |
| Comments: |
CTP, UTP and GTP can act as donors. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9026-55-5 |
| References: |
| 1. |
Lewin, L.M. and Brown, G.M. The biosynthesis of thiamine. III. Mechanism of enzymatic formation of the pyrophosphate ester of 2-methyl-4-amino-5-hydroxymethylpyrimidine. J. Biol. Chem. 236 (1961) 2768–2771. |
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| [EC 2.7.1.49 created 1965] |
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