ExplorEnz: EC 2.7.1.230

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2.7.1.230

Accepted name:

amicoumacin kinase

Reaction:

ATP + amicoumacin A = ADP + amicoumacin A 2-phosphate

Other name(s):

amiN (gene name); yerI (gene name)

Systematic name:

ATP:amicoumacin A 2-phosphotransferase

Comments:

The enzyme, found in some bacterial species, inactivates the antibiotic amicoumacin A by phosphorylating it, conferring resistance on the bacteria.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc, PDB

References:

Terekhov, S.S., Smirnov, I.V., Malakhova, M.V., Samoilov, A.E., Manolov, A.I., Nazarov, A.S., Danilov, D.V., Dubiley, S.A., Osterman, I.A., Rubtsova, M.P., Kostryukova, E.S., Ziganshin, R.H., Kornienko, M.A., Vanyushkina, A.A., Bukato, O.N., Ilina, E.N., Vlasov, V.V., Severinov, K.V., Gabibov, A.G. and Altman, S. Ultrahigh-throughput functional profiling of microbiota communities. Proc. Natl. Acad. Sci. USA 115 (2018) 9551–9556. [PMID: 30181282]

[EC 2.7.1.230 created 2019]