ExplorEnz: EC 2.6.1.111

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2.6.1.111

Accepted name:

3-aminobutanoyl-CoA transaminase

Reaction:

3-aminobutanoyl-CoA + 2-oxoglutarate = acetoacetyl-CoA + L-glutamate

Other name(s):

kat (gene name); acyl-CoA β-transaminase

Systematic name:

3-aminobutanoyl-CoA:2-oxoglutarate aminotransferase

Comments:

The enzyme, found in bacteria, is part of a L-lysine degradation pathway. The enzyme is also active with other β-amino compounds such as 3-amino-5-methylhexanoyl-CoA and 3-amino-3-phenylpropanoyl-CoA.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc

References:

1.	Perret, A., Lechaplais, C., Tricot, S., Perchat, N., Vergne, C., Pelle, C., Bastard, K., Kreimeyer, A., Vallenet, D., Zaparucha, A., Weissenbach, J. and Salanoubat, M. A novel acyl-CoA β-transaminase characterized from a metagenome. PLoS One 6:e22918 (2011). [DOI] [PMID: 21826218]

[EC 2.6.1.111 created 2017]