| EC |
2.5.1.88 |
| Accepted name: |
trans,polycis-polyprenyl diphosphate synthase [(2Z,6E)-farnesyl diphosphate specific] |
| Reaction: |
(2Z,6E)-farnesyl diphosphate + n isopentenyl diphosphate = n diphosphate + trans,polycis-polyprenyl diphosphate (n = 9–11) |
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For diagram of trans-polycis-polyprenol diphosphate biosynthesis, click here |
| Systematic name: |
(2Z,6E)-farnesyl-diphosphate:isopentenyl-diphosphate cistransferase (adding 9–11 isopentenyl units) |
| Comments: |
Highest activity with (2Z,6E)-farnesyl diphosphate as allylic substrate. Broad product specificity with the major product being dodecaprenyl diphosphate. Synthesizes even C70 prenyl diphosphate as the maximum chain-length product [1]. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Ambo, T., Noike, M., Kurokawa, H. and Koyama, T. Cloning and functional analysis of cis-prenyltransferase from Thermobifida fusca. J. Biosci. Bioeng. 107 (2009) 620–622. [DOI] [PMID: 19447338] |
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| [EC 2.5.1.88 created 2010] |
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