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Your query returned 1 entry. Printable version
EC | 2.5.1.107 | ||
Accepted name: | verruculogen prenyltransferase | ||
Reaction: | prenyl diphosphate + verruculogen = diphosphate + fumitremorgin A | ||
For diagram of fumitremorgin alkaloid biosynthesis (part 2), click here | |||
Glossary: | prenyl diphosphate = dimethylallyl diphosphate verruculogen = (5R,10S,10aR,14aS,15bS)-10,10a-dihydroxy-6-methoxy-2,2-dimethyl-5-(2-methylprop-1-en-1-yl)-1,10,10a,14,14a,15b-hexahydro-12H-3,4-dioxa-5a,11a,15a-triazacycloocta[1,2,3-lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione fumitremorgin A = (5R,10S,10aR,14aS,15bS)-10a-hydroxy-7-methoxy-2,2-dimethyl-10-[(3-methylbut-2-en-1-yl)oxy]-5-(2-methylprop-1-en-1-yl)-1,10,10a,14,14a,15b-hexahydro-12H-3,4-dioxa-5a,11a,15a-triazacycloocta[1,2,3-lm]indeno[5,6-b]fluorene-11,15(H,13H)-dione |
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Other name(s): | FtmPT3; dimethylallyl-diphosphate:verruculogen dimethylallyl-O-transferase | ||
Systematic name: | prenyl-diphosphate:verruculogen dimethylallyl-O-transferase | ||
Comments: | Found in a number of fungi. Catalyses the last step in the biosynthetic pathway of the indole alkaloid fumitremorgin A. The enzyme from the fungus Neosartorya fischeri is also active with fumitremorgin B and 12α,13α-dihydroxyfumitremorgin C. | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
References: |
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