EC |
2.4.2.55 |
Accepted name: |
nicotinate D-ribonucleotide:phenol phospho-D-ribosyltransferase |
Reaction: |
nicotinate D-ribonucleotide + phenol = nicotinate + phenyl 5-phospho-α-D-ribofuranoside |
Other name(s): |
ArsAB |
Systematic name: |
nicotinate D-ribonucleotide:phenol phospho-D-ribosyltransferase |
Comments: |
The enzyme is involved in the biosynthesis of phenolic cobamides in the Gram-positive bacterium Sporomusa ovata. It can also transfer the phospho-D-ribosyl group to 4-methylphenol and 5,6-dimethylbenzimidazole. The related EC 2.4.2.21, nicotinate-nucleotide dimethylbenzimidazole phosphoribosyltransferase, also transfers the phospho-D-ribosyl group from nicotinate D-ribonucleotide to 5,6-dimethylbenzimidazole, but shows no activity with 4-methylphenol or phenol. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Chan, C.H. and Escalante-Semerena, J.C. ArsAB, a novel enzyme from Sporomusa ovata activates phenolic bases for adenosylcobamide biosynthesis. Mol. Microbiol. 81 (2011) 952–967. [DOI] [PMID: 21696461] |
|
[EC 2.4.2.55 created 2013] |
|
|
|
|