ExplorEnz: EC 2.4.1.367

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2.4.1.367

Accepted name:

ginsenoside 6-O-glucosyltransferase

Reaction:

(1) UDP-α-D-glucose + protopanaxatriol = UDP + ginsenoside Rh1
(2) UDP-α-D-glucose + ginsenoside F1 = UDP + (20S)-ginsenoside Rg1

Glossary:

protopanaxatriol = (3β,6α,12β)-dammar-24-ene-3,6,12,20-tetrol
ginsenoside F1 = (3β,6α,12β)-trihydroxydammar-24-en-20-yl β-D-glucopyranoside

Other name(s):

UGTPg100 (gene name)

Systematic name:

UDP-α-D-glucose:ginsenoside 6-O-glucosyltransferase

Comments:

The enzyme, characterized from the plant Panax ginseng, glucosylates the C-6 position of protopanaxatriol and ginsenoside F1.

Links to other databases:

BRENDA, EXPASY, KEGG, MetaCyc

References:

Wei, W., Wang, P., Wei, Y., Liu, Q., Yang, C., Zhao, G., Yue, J., Yan, X. and Zhou, Z. Characterization of Panax ginseng UDP-glycosyltransferases catalyzing protopanaxatriol and biosyntheses of bioactive ginsenosides F1 and Rh1 in metabolically engineered yeasts. Mol. Plant 8 (2015) 1412–1424. [PMID: 26032089]

[EC 2.4.1.367 created 2019]