The Enzyme Database

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Accepted name: chalcone 4′-O-glucosyltransferase
Reaction: (1) UDP-α-D-glucose + naringenin chalcone = UDP + 2′,4,4′,6′-tetrahydroxychalcone 4′-O-β-D-glucoside
(2) UDP-α-D-glucose + 2′,3,4,4′,6′-pentahydroxychalcone = UDP + 2′,3,4,4′,6′-pentahydroxychalcone 4′-O-β-D-glucoside
For diagram of aureusidin biosynthesis, click here
Glossary: naringenin chalcone = 2′,4,4′,6′-tetrahydroxychalcone = 3-(4-hydroxyphemyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one
Other name(s): 4′CGT
Systematic name: UDP-α-D-glucose:2′,4,4′,6′-tetrahydroxychalcone 4′-O-β-D-glucosyltransferase
Comments: Isolated from the plant Antirrhinum majus (snapdragon). Involved in the biosynthesis of aurones, plant flavonoids that provide yellow color to the flowers.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Ono, E., Fukuchi-Mizutani, M., Nakamura, N., Fukui, Y., Yonekura-Sakakibara, K., Yamaguchi, M., Nakayama, T., Tanaka, T., Kusumi, T. and Tanaka, Y. Yellow flowers generated by expression of the aurone biosynthetic pathway. Proc. Natl. Acad. Sci. USA 103 (2006) 11075–11080. [DOI] [PMID: 16832053]
[EC created 2012]

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