| EC |
2.4.1.285 |
| Accepted name: |
UDP-GlcNAc:ribostamycin N-acetylglucosaminyltransferase |
| Reaction: |
UDP-N-acetyl-α-D-glucosamine + ribostamycin = UDP + 2′′′-acetyl-6′′′-hydroxyneomycin C |
| Other name(s): |
neoK (gene name) |
| Systematic name: |
UDP-N-acetyl-α-D-glucosamine:ribostamycin N-acetylglucosaminyltransferase |
| Comments: |
Involved in biosynthesis of the aminoglycoside antibiotic neomycin. Requires a divalent metal ion, optimally Mg2+, Mn2+ or Co2+. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Yokoyama, K., Yamamoto, Y., Kudo, F. and Eguchi, T. Involvement of two distinct N-acetylglucosaminyltransferases and a dual-function deacetylase in neomycin biosynthesis. ChemBioChem 9 (2008) 865–869. [DOI] [PMID: 18311744] |
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| [EC 2.4.1.285 created 2012] |
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