| EC |
2.3.1.5 |
| Accepted name: |
arylamine N-acetyltransferase |
| Reaction: |
acetyl-CoA + an arylamine = CoA + an N-acetylarylamine |
| Other name(s): |
arylamine acetylase; β-naphthylamine N-acetyltransferase; 4-aminobiphenyl N-acetyltransferase; acetyl CoA-arylamine N-acetyltransferase; 2-naphthylamine N-acetyltransferase; arylamine acetyltransferase; indoleamine N-acetyltransferase; N-acetyltransferase (ambiguous); p-aminosalicylate N-acetyltransferase; serotonin acetyltransferase; serotonin N-acetyltransferase |
| Systematic name: |
acetyl-CoA:arylamine N-acetyltransferase |
| Comments: |
Wide specificity for aromatic amines, including serotonin; also catalyses acetyl-transfer between arylamines without CoA. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, Gene, GTD, KEGG, MetaCyc, PDB, CAS registry number: 9027-33-2 |
| References: |
| 1. |
Chou, T.C. and Lipmann, F. Separation of acetyl transfer enzymes in pigeon liver extract. J. Biol. Chem. 196 (1952) 89–103. [PMID: 12980945] |
| 2. |
Paul, R.C. and Ratledge, C. Further studies on anthranilate N-acetylanthranilic acid in Aerobacter aerogenes. Biochim. Biophys. Acta 320 (1973) 9–15. [DOI] [PMID: 4748369] |
| 3. |
Tabor, H., Mehler, A.H. and Stadtman, E.R. The enzymatic acetylation of amines. J. Biol. Chem. 204 (1953) 127–138. [PMID: 13084583] |
| 4. |
Weissbach, H., Redfield, B.G. and Axelrod, J. The enzymic acetylation of serotonin and other naturally occurring amines. Biochim. Biophys. Acta 54 (1961) 190–192. [DOI] [PMID: 14005907] |
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| [EC 2.3.1.5 created 1961] |
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