| EC |
2.1.2.3 |
| Accepted name: |
phosphoribosylaminoimidazolecarboxamide formyltransferase |
| Reaction: |
10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide |
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For diagram of the late stages of purine biosynthesis, click here |
| Other name(s): |
5-amino-4-imidazolecarboxamide ribonucleotide transformylase; AICAR transformylase; 10-formyltetrahydrofolate:5′-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase; 5′-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase; 5-amino-1-ribosyl-4-imidazolecarboxamide 5′-phosphate transformylase; 5-amino-4-imidazolecarboxamide ribotide transformylase; AICAR formyltransferase; aminoimidazolecarboxamide ribonucleotide transformylase |
| Systematic name: |
10-formyltetrahydrofolate:5′-phosphoribosyl-5-amino-4-imidazole-carboxamide N-formyltransferase |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9032-03-5 |
| References: |
| 1. |
Hartman, S.C. and Buchanan, J.M. Biosynthesis of the purines. XXVI. The identification of the formyl donors of the transformylation reaction. J. Biol. Chem. 234 (1959) 1812–1816. [PMID: 13672969] |
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| [EC 2.1.2.3 created 1961, modified 2000] |
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