EC |
2.1.1.97 |
Accepted name: |
3-hydroxyanthranilate 4-C-methyltransferase |
Reaction: |
S-adenosyl-L-methionine + 3-hydroxyanthranilate = S-adenosyl-L-homocysteine + 3-hydroxy-4-methylanthranilate |
Other name(s): |
3-hydroxyanthranilate 4-methyltransferase |
Systematic name: |
S-adenosyl-L-methionine:3-hydroxyanthranilate 4-C-methyltransferase |
Comments: |
Involved in the biosynthesis of the antibiotic actinomycin in Streptomyces antibioticus. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 112445-22-4 |
References: |
1. |
Fawaz, F. and Jones, G.H. Actinomycin synthesis in Streptomyces antibioticus. Purification and properties of a 3-hydroxyanthranilate 4-methyltransferase. J. Biol. Chem. 263 (1988) 4602–4606. [PMID: 2450873] |
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[EC 2.1.1.97 created 1990] |
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