EC |
2.1.1.84 |
Accepted name: |
methylquercetagetin 6-O-methyltransferase |
Reaction: |
S-adenosyl-L-methionine + 5,6,3′,4′-tetrahydroxy-3,7-dimethoxyflavone = S-adenosyl-L-homocysteine + 5,3′,4′-trihydroxy-3,6,7-trimethoxyflavone |
Other name(s): |
flavonol 6-O-methyltransferase; flavonol 6-methyltransferase; 6-OMT; S-adenosyl-L-methionine:3′,4′,5,6-tetrahydroxy-3,7-dimethoxyflavone 6-O-methyltransferase |
Systematic name: |
S-adenosyl-L-methionine:5,6,3′,4′-tetrahydroxy-3,7-dimethoxyflavone 6-O-methyltransferase |
Comments: |
The enzymes from Chrysosplenium americanum also methylates 3,7,3′-trimethylquercetagetin at the 6-position. Does not act on flavones, dihydroflavonols, or their glucosides. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 97089-68-4 |
References: |
1. |
De Luca, V. and Ibrahim, R.K. Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. I. Partial purification and some properties of S-adenosyl-L-methionine:flavonol 3-, 6-, 7-, and 4′-O-methyltransferases. Arch. Biochem. Biophys. 238 (1985) 596–605. [DOI] [PMID: 3994393] |
2. |
De Luca, V. and Ibrahim, R.K. Enzymatic synthesis of polymethylated flavonols in Chrysosplenium americanum. II. Substrate interaction and product inhibition studies of flavonol 3-, 6-, and 4′-O-methyltransferases. Arch. Biochem. Biophys. 238 (1985) 606–618. [DOI] [PMID: 3994394] |
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[EC 2.1.1.84 created 1989] |
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