| EC |
2.1.1.205 |
| Accepted name: |
tRNA (cytidine32/guanosine34-2′-O)-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + cytidine32/guanosine34 in tRNA = S-adenosyl-L-homocysteine + 2′-O-methylcytidine32/2′-O-methylguanosine34 in tRNA |
| Other name(s): |
Trm7p |
| Systematic name: |
S-adenosyl-L-methionine:tRNA (cytidine32/guanosine34-2′-O)-methyltransferase |
| Comments: |
The enzyme from Saccharomyces cerevisiae catalyses the formation of 2′-O-methylnucleotides at positions 32 and 34 of the yeast tRNAPhe, tRNATrp and, possibly, tRNALeu. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Pintard, L., Lecointe, F., Bujnicki, J.M., Bonnerot, C., Grosjean, H. and Lapeyre, B. Trm7p catalyses the formation of two 2′-O-methylriboses in yeast tRNA anticodon loop. EMBO J. 21 (2002) 1811–1820. [DOI] [PMID: 11927565] |
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| [EC 2.1.1.205 created 2011] |
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