| EC |
2.1.1.174 |
| Accepted name: |
23S rRNA (guanine1835-N2)-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + guanine1835 in 23S rRNA = S-adenosyl-L-homocysteine + N2-methylguanine1835 in 23S rRNA |
| Other name(s): |
ygjO (gene name); rlmG (gene name); ribosomal RNA large subunit methyltransferase G |
| Systematic name: |
S-adenosyl-L-methionine:23S rRNA (guanine1835-N2)-methyltransferase |
| Comments: |
The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate [1]. The enzyme specifically methylates guanine1835 at N2 in 23S rRNA. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Sergiev, P.V., Lesnyak, D.V., Bogdanov, A.A. and Dontsova, O.A. Identification of Escherichia coli m2G methyltransferases: II. The ygjO gene encodes a methyltransferase specific for G1835 of the 23 S rRNA. J. Mol. Biol. 364 (2006) 26–31. [DOI] [PMID: 17010380] |
|
| [EC 2.1.1.174 created 1976 as EC 2.1.1.52, part transferred 2010 to EC 2.1.1.174] |
| |
|
| |
|
Printable version