| EC |
1.7.6.1 |
| Accepted name: |
nitrite dismutase |
| Reaction: |
3 nitrite + 2 H+ = 2 nitric oxide + nitrate + H2O |
| Other name(s): |
Prolixin S; Nitrophorin 7 |
| Systematic name: |
nitrite:nitrite oxidoreductase |
| Comments: |
Contains ferriheme b. The enzyme is one of the nitrophorins from the salivary gland of the blood-feeding insect Rhodnius prolixus. Nitric oxide produced induces vasodilation after injection. Nitrophorins 2 and 4 can also catalyse this reaction. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
He, C. and Knipp, M. Formation of nitric oxide from nitrite by the ferriheme b protein nitrophorin 7. J. Am. Chem. Soc. 131 (2009) 12042–12043. [DOI] [PMID: 19655755] |
| 2. |
He, C., Ogata, H. and Knipp, M. Formation of the complex of nitrite with the ferriheme b β-barrel proteins nitrophorin 4 and nitrophorin 7. Biochemistry 49 (2010) 5841–5851. [DOI] [PMID: 20524697] |
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| [EC 1.7.6.1 created 2011] |
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