| EC |
1.5.3.19 |
| Accepted name: |
4-methylaminobutanoate oxidase (formaldehyde-forming) |
| Reaction: |
4-methylaminobutanoate + O2 + H2O = 4-aminobutanoate + formaldehyde + H2O2 |
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For diagram of nicotine catabolism by arthrobacter, click here |
| Other name(s): |
mabO (gene name) |
| Systematic name: |
4-methylaminobutanoate:oxygen oxidoreductase (formaldehyde-forming) |
| Comments: |
A flavoprotein (FAD). In the enzyme from the soil bacterium Arthrobacter nicotinovorans the cofactor is covalently bound. Participates in the nicotine degradation pathway of this organism. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, KEGG, MetaCyc |
| References: |
| 1. |
Chiribau, C.B., Sandu, C., Fraaije, M., Schiltz, E. and Brandsch, R. A novel γ-N-methylaminobutyrate demethylating oxidase involved in catabolism of the tobacco alkaloid nicotine by Arthrobacter nicotinovorans pAO1. Eur. J. Biochem. 271 (2004) 4677–4684. [DOI] [PMID: 15606755] |
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| [EC 1.5.3.19 created 2012] |
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