| EC |
1.5.3.14 |
| Accepted name: |
polyamine oxidase (propane-1,3-diamine-forming) |
| Reaction: |
spermidine + O2 + H2O = propane-1,3-diamine + 4-aminobutanal + H2O2 |
| Other name(s): |
MPAO (ambiguous); maize PAO |
| Systematic name: |
spermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) |
| Comments: |
As the products of the reaction cannot be converted directly to other polyamines, this class of polyamine oxidases is considered to be involved in the terminal catabolism of polyamines [1]. This enzyme less efficiently catalyses the oxidation of N1-acetylspermine and spermine. A flavoprotein (FAD). Differs in specificity from EC 1.5.3.13 (N1-acetylpolyamine oxidase), EC 1.5.3.15 [N8-acetylspermidine oxidase (propane-1,3-diamine-forming)], EC 1.5.3.16 (spermine oxidase) and EC 1.5.3.17 (non-specific polyamine oxidase). |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Tavladoraki, P., Schinina, M.E., Cecconi, F., Di Agostino, S., Manera, F., Rea, G., Mariottini, P., Federico, R. and Angelini, R. Maize polyamine oxidase: primary structure from protein and cDNA sequencing. FEBS Lett. 426 (1998) 62–66. [DOI] [PMID: 9598979] |
| 2. |
Federico, R., Ercolini, L., Laurenzi, M., Angelini, R. Oxidation of acetylpolyamines by maize polyamine oxidase. Phytochemistry 43 (1996) 339–341. |
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| [EC 1.5.3.14 created 2009] |
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