The Enzyme Database

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Accepted name: 8-hydroxy-5-deazaflavin:NADPH oxidoreductase
Reaction: reduced coenzyme F420 + NADP+ = oxidized coenzyme F420 + NADPH + H+
For diagram of coenzyme F420 biosynthesis, click here
Other name(s): 8-OH-5dFl:NADPH oxidoreductase
Systematic name: reduced coenzyme F420:NADP+ oxidoreductase
Comments: The enzyme has an absolute requirement for both the 5-deazaflavin structure and the presence of an 8-hydroxy group in the substrate [1].
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB
1.  Eker, A.P., Hessels, J.K. and Meerwaldt, R. Characterization of an 8-hydroxy-5-deazaflavin:NADPH oxidoreductase from Streptomyces griseus. Biochim. Biophys. Acta 990 (1989) 80–86. [DOI] [PMID: 2492438]
[EC created 2011]

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