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Your query returned 1 entry. Printable version
EC | 1.4.1.14 | ||||||||||
Accepted name: | glutamate synthase (NADH) | ||||||||||
Reaction: | 2 L-glutamate + NAD+ = L-glutamine + 2-oxoglutarate + NADH + H+ (1a) L-glutamate + NH3 = L-glutamine + H2O (1b) L-glutamate + NAD+ + H2O = NH3 + 2-oxoglutarate + NADH + H+ |
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Other name(s): | glutamate (reduced nicotinamide adenine dinucleotide) synthase; NADH: GOGAT; L-glutamate synthase (NADH); L-glutamate synthetase; NADH-glutamate synthase; NADH-dependent glutamate synthase | ||||||||||
Systematic name: | L-glutamate:NAD+ oxidoreductase (transaminating) | ||||||||||
Comments: | A flavoprotein (FMN). The reaction takes place in the direction of L-glutamate production. The protein is composed of two domains, one hydrolysing L-glutamine to NH3 and L-glutamate (cf. EC 3.5.1.2, glutaminase), the other combining the produced NH3 with 2-oxoglutarate to produce a second molecule of L-glutamate (cf. EC 1.4.1.2, glutamate dehydrogenase). | ||||||||||
Links to other databases: | BRENDA, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 65589-88-0 | ||||||||||
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