| EC |
1.20.4.3 |
| Accepted name: |
mycoredoxin |
| Reaction: |
arseno-mycothiol + mycoredoxin = arsenite + mycothiol-mycoredoxin disulfide |
| Glossary: |
mycothiol = 1-O-[2-(N2-acetyl-L-cysteinamido)-2-deoxy-α-D-glucopyranosyl]-1D-myo-inositol |
| Other name(s): |
Mrx1; MrxI |
| Systematic name: |
arseno-mycothiol:mycoredoxin oxidoreductase |
| Comments: |
Reduction of arsenate is part of a defense mechanism of the cell against toxic arsenate. The substrate arseno-mycothiol is formed by EC 2.8.4.2 (arsenate:mycothiol transferase). A second mycothiol recycles mycoredoxin and forms mycothione. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, PDB |
| References: |
| 1. |
Ordonez, E., Van Belle, K., Roos, G., De Galan, S., Letek, M., Gil, J.A., Wyns, L., Mateos, L.M. and Messens, J. Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchange. J. Biol. Chem. 284 (2009) 15107–15116. [DOI] [PMID: 19286650] |
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| [EC 1.20.4.3 created 2010] |
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