The Enzyme Database

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EC 1.2.99.10     
Accepted name: 4,4′-diapolycopenoate synthase
Reaction: (1) 4,4′-diapolycopen-4-al + H2O + acceptor = 4,4′-diapolycopen-4-oate + reduced acceptor
(2) 4,4′-diapolycopene-4,4′-dial + 2 H2O + 2 acceptor = 4,4′-diapolycopene-4,4′-dioate + 2 reduced acceptor
For diagram of C30 carotenoid biosynthesis, click here
Other name(s): crtNc; 4,4′-diapolycopenealdehyde oxidase (misleading)
Systematic name: 4,4′-diapolycopen-4-al,donor:oxygen oxidoreductase (4,4′-diapolycopen-4-oate-forming)
Comments: The enzyme has been described from the bacteria Methylomonas sp. 16a and Bacillus indicus.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
References:
1.  Tao, L., Schenzle, A., Odom, J.M. and Cheng, Q. Novel carotenoid oxidase involved in biosynthesis of 4,4′-diapolycopene dialdehyde. Appl. Environ. Microbiol. 71 (2005) 3294–3301. [DOI] [PMID: 15933032]
2.  Steiger, S., Perez-Fons, L., Cutting, S.M., Fraser, P.D. and Sandmann, G. Annotation and functional assignment of the genes for the C30 carotenoid pathways from the genomes of two bacteria: Bacillus indicus and Bacillus firmus. Microbiology 161 (2015) 194–202. [DOI] [PMID: 25326460]
[EC 1.2.99.10 created 2017]
 
 


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