The Enzyme Database

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Accepted name: 2-hydroxy-2-methylpropanal dehydrogenase
Reaction: 2-hydroxy-2-methylpropanal + NAD+ + H2O = 2-hydroxy-2-methylpropanoate + NADH + H+
Other name(s): mpdC (gene name)
Systematic name: 2-hydroxy-2-methylpropanal:NAD+ oxidoreductase
Comments: This bacterial enzyme is involved in the degradation pathways of the alkene 2-methylpropene and the fuel additive tert-butyl methyl ether (MTBE), a widely occurring groundwater contaminant.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc
1.  Lopes Ferreira, N., Labbe, D., Monot, F., Fayolle-Guichard, F. and Greer, C.W. Genes involved in the methyl tert-butyl ether (MTBE) metabolic pathway of Mycobacterium austroafricanum IFP 2012. Microbiology 152 (2006) 1361–1374. [DOI] [PMID: 16622053]
[EC created 2016]

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