EC |
1.2.1.81 |
Accepted name: |
sulfoacetaldehyde dehydrogenase (acylating) |
Reaction: |
2-sulfoacetaldehyde + CoA + NADP+ = sulfoacetyl-CoA + NADPH + H+ |
Glossary: |
2-sulfoacetaldehyde = 2-oxoethanesulfonate |
Other name(s): |
SauS |
Systematic name: |
2-sulfoacetaldehyde:NADP+ oxidoreductase (CoA-acetylating) |
Comments: |
The enzyme is involved in degradation of sulfoacetate. In this pathway the reaction is catalysed in the reverse direction. The enzyme is specific for sulfoacetaldehyde and NADP+. |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Weinitschke, S., Hollemeyer, K., Kusian, B., Bowien, B., Smits, T.H. and Cook, A.M. Sulfoacetate is degraded via a novel pathway involving sulfoacetyl-CoA and sulfoacetaldehyde in Cupriavidus necator H16. J. Biol. Chem. 285 (2010) 35249–35254. [DOI] [PMID: 20693281] |
|
[EC 1.2.1.81 created 2011] |
|
|
|
|