| EC |
1.14.15.1 |
| Accepted name: |
camphor 5-monooxygenase |
| Reaction: |
(+)-camphor + reduced putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O |
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For diagram of camphor catabolism, click here |
| Other name(s): |
camphor 5-exo-methylene hydroxylase; 2-bornanone 5-exo-hydroxylase; bornanone 5-exo-hydroxylase; camphor 5-exo-hydroxylase; camphor 5-exohydroxylase; camphor hydroxylase; d-camphor monooxygenase; methylene hydroxylase; methylene monooxygenase; D-camphor-exo-hydroxylase; camphor methylene hydroxylase |
| Systematic name: |
(+)-camphor,reduced putidaredoxin:oxygen oxidoreductase (5-hydroxylating) |
| Comments: |
A heme-thiolate protein (P-450). Also acts on (-)-camphor and 1,2-campholide, forming 5-exo-hydroxy-1,2-campholide. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 9030-82-4 |
| References: |
| 1. |
Hedegaard, J. and Gunsalus, I.C. Mixed function oxidation. IV. An induced methylene hydroxylase in camphor oxidation. J. Biol. Chem. 240 (1965) 4038–4043. [PMID: 4378858] |
| 2. |
Tyson, C.A., Lipscomb, J.D. and Gunsalus, I.C. The role of putidaredoxin and P450cam in methylene hydroxylation. J. Biol. Chem. 247 (1972) 5777–5784. [PMID: 4341491] |
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| [EC 1.14.15.1 created 1972, modified 1986] |
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