| EC |
1.14.14.92 |
| Accepted name: |
benzoate 4-monooxygenase |
| Reaction: |
benzoate + [reduced NADPH—hemoprotein reductase] + O2 = 4-hydroxybenzoate + [oxidized NADPH—hemoprotein reductase] + H2O |
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For diagram of benzoate metabolism, click here |
| Other name(s): |
benzoic acid 4-hydroxylase; benzoate 4-hydroxylase; benzoic 4-hydroxylase; benzoate-p-hydroxylase; p-hydroxybenzoate hydroxylase; CYP53A1 (gene name) |
| Systematic name: |
benzoate,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (4-hydroxylating) |
| Comments: |
A cytochrome P-450 (heme-thiolate) protein found in Aspergillus fungi. |
| Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 39391-25-8 |
| References: |
| 1. |
Reddy, C.C. and Vaidyanathan, C.S. Purification, properties and induction of a specific benzoate-4-hydroxylase from Aspergillus niger (UBC 814). Biochim. Biophys. Acta 384 (1975) 46–57. [DOI] [PMID: 236777] |
| 2. |
Faber, B.W., van Gorcom, R.F. and Duine, J.A. Purification and characterization of benzoate-para-hydroxylase, a cytochrome P450 (CYP53A1), from Aspergillus niger. Arch. Biochem. Biophys. 394 (2001) 245–254. [PMID: 11594739] |
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| [EC 1.14.14.92 created 1976 as EC 1.14.13.12, transferred 2018 to EC 1.14.14.92] |
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