EC |
1.14.14.62 |
Accepted name: |
salviol synthase |
Reaction: |
ferruginol + [reduced NADPH—hemoprotein reductase] + O2 = salviol + [oxidized NADPH—hemoprotein reductase] + H2O |
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For diagram of carnosic acid, salviol and suginol diterpenoids biosynthesis, click here |
Glossary: |
salviol = abieta-8,11,13-triene-2α,12-diol |
Other name(s): |
CYP71BE52 |
Systematic name: |
ferruginol,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (salviol-forming) |
Comments: |
A cytochrome P-450 (heme-thiolate) protein isolated from the plant Salvia pomifera (apple sage). |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Ignea, C., Athanasakoglou, A., Ioannou, E., Georgantea, P., Trikka, F.A., Loupassaki, S., Roussis, V., Makris, A.M. and Kampranis, S.C. Carnosic acid biosynthesis elucidated by a synthetic biology platform. Proc. Natl. Acad. Sci. USA 113 (2016) 3681–3686. [DOI] [PMID: 26976595] |
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[EC 1.14.14.62 created 2018] |
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