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Your query returned 1 entry. 
Printable version
| EC | 1.14.14.125 | ||
| Accepted name: | monacolin L hydroxylase | ||
| Reaction: | monacolin L acid + O2 + [reduced NADPH—hemoprotein reductase] = monacolin J acid + [oxidized NADPH—hemoprotein reductase] + H2O | ||
| For diagram of lovastatin biosynthesis, click here | |||
| Glossary: | monacolin L acid = (3R,5R)-7-[(1S,2S,6R,8aR)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid monacolin J acid = (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-hydroxy-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid |
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| Other name(s): | LovA (ambiguous) | ||
| Systematic name: | monacolin L acid,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (8-hydroxylating) | ||
| Comments: | A cytochrome P-450 (heme-thiolate) protein. The enzyme from fungi also catalyses the reaction of EC 1.14.14.124, dihydromonacolin L hydroxylase. | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
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