EC |
1.14.13.24 |
Accepted name: |
3-hydroxybenzoate 6-monooxygenase |
Reaction: |
3-hydroxybenzoate + NADH + H+ + O2 = 2,5-dihydroxybenzoate + NAD+ + H2O |
Other name(s): |
3-hydroxybenzoate 6-hydroxylase; m-hydroxybenzoate 6-hydroxylase; 3-hydroxybenzoic acid-6-hydroxylase |
Systematic name: |
3-hydroxybenzoate,NADH:oxygen oxidoreductase (6-hydroxylating) |
Comments: |
A flavoprotein (FAD). Acts also on a number of analogues of 3-hydroxybenzoate substituted in the 2, 4, 5 and 6 positions; NADPH can act instead of NADH, but more slowly. |
Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 51570-26-4 |
References: |
1. |
Groseclose, E.E. and Ribbons, D.W. 3-Hydroxybenzoate 6-hydroxylase from Pseudomonas aeruginosa. Biochem. Biophys. Res. Commun. 55 (1973) 897–903. [DOI] [PMID: 4357436] |
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[EC 1.14.13.24 created 1984] |
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