EC |
1.14.13.10 |
Accepted name: |
2,6-dihydroxypyridine 3-monooxygenase |
Reaction: |
2,6-dihydroxypyridine + NADH + H+ + O2 = 2,3,6-trihydroxypyridine + NAD+ + H2O |
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For diagram of nicotine catabolism by arthrobacter, click here |
Other name(s): |
2,6-dihydroxypyridine oxidase |
Systematic name: |
2,6-dihydroxypyridine,NADH:oxygen oxidoreductase (3-hydroxylating) |
Comments: |
A flavoprotein. |
Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 39279-38-4 |
References: |
1. |
Holmes, P.E. and Rittenberg, S.C. The bacterial oxidation of nicotine. VII. Partial purification and properties of 2,6-dihydroxypyridine oxidase. J. Biol. Chem. 247 (1972) 7622–7627. [PMID: 4344227] |
2. |
Holmes, P.E., Rittenberg, S.C. and Knackmuss, H.J. The bacterial oxidation of nicotine. 8. Synthesis of 2,3,6-trihydroxypyridine and accumulation and partial characterization of the product of 2,6-dihydroxypyridine oxidation. J. Biol. Chem. 247 (1972) 7628–7633. [PMID: 4636328] |
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[EC 1.14.13.10 created 1976] |
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