EC |
1.14.12.1 |
Accepted name: |
anthranilate 1,2-dioxygenase (deaminating, decarboxylating) |
Reaction: |
anthranilate + NAD(P)H + 2 H+ + O2 = catechol + CO2 + NAD(P)+ + NH3 |
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For diagram of reaction, click here |
Other name(s): |
anthranilate hydroxylase; anthranilic hydroxylase; anthranilic acid hydroxylase |
Systematic name: |
anthranilate,NAD(P)H:oxygen oxidoreductase (1,2-hydroxylating, deaminating, decarboxylating) |
Comments: |
Requires Fe2+. |
Links to other databases: |
BRENDA, EAWAG-BBD, EXPASY, Gene, KEGG, MetaCyc, CAS registry number: 9059-17-0 |
References: |
1. |
Kobayashi, S. and Hayaishi, O. Anthranilic acid conversion to catechol (Pseudomonas). Methods Enzymol. 17A (1970) 505–510. |
2. |
Taniguchi, H., Hatanaka, M., Kuno, S., Hayaishi, O., Nakajima, M. and Kurihara, N. Enzymatic formation of catechol from anthranilic acid. J. Biol. Chem. 239 (1964) 2204–2211. [PMID: 14209949] |
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[EC 1.14.12.1 created 1972] |
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