| EC |
1.14.11.11 |
| Accepted name: |
hyoscyamine (6S)-dioxygenase |
| Reaction: |
L-hyoscyamine + 2-oxoglutarate + O2 = (6S)-hydroxyhyoscyamine + succinate + CO2 |
|
For diagram of tropane alkaloid biosynthesis, click here |
| Other name(s): |
hyoscyamine 6β-hydroxylase; hyoscyamine 6β-dioxygenase; hyoscyamine 6-hydroxylase |
| Systematic name: |
L-hyoscyamine,2-oxoglutarate:oxygen oxidoreductase [(6S)-hydroxylating] |
| Comments: |
Requires Fe2+ and ascorbate. |
| Links to other databases: |
BRENDA, EXPASY, Gene, KEGG, MetaCyc, PDB, CAS registry number: 103865-33-4 |
| References: |
| 1. |
Hashimoto, T. and Yamada, Y. Hyoscyamine 6β-hydroxylase, a 2-oxoglutarate-dependent dioxygenase, in alkaloid-producing root cultures. Plant Physiol. 81 (1986) 619–625. [PMID: 16664866] |
|
| [EC 1.14.11.11 created 1989] |
| |
|
| |
|
Printable version