| EC |
1.14.11.10 |
| Accepted name: |
pyrimidine-deoxynucleoside 1′-dioxygenase |
| Reaction: |
2′-deoxyuridine + 2-oxoglutarate + O2 = uracil + 2-deoxyribonolactone + succinate + CO2 |
| Other name(s): |
deoxyuridine-uridine 1′-dioxygenase |
| Systematic name: |
2′-deoxyuridine,2-oxoglutarate:oxygen oxidoreductase (1′-hydroxylating) |
| Comments: |
Requires iron(II) and ascorbate. cf. EC 1.14.11.3, pyrimidine-deoxynucleoside 2′-dioxygenase. |
| Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 98865-52-2 |
| References: |
| 1. |
Stubbe, J. Identification of two α-ketoglutarate-dependent dioxygenases in extracts of Rhodotorula glutinis catalyzing deoxyuridine hydroxylation. J. Biol. Chem. 260 (1985) 9972–9975. [PMID: 4040518] |
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| [EC 1.14.11.10 created 1989, modified 2002] |
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