The Enzyme Database

Your query returned 1 entry.    printer_iconPrintable version

Accepted name: 2-amino-5-chlorophenol 1,6-dioxygenase
Reaction: 2-amino-5-chlorophenol + O2 = 2-amino-5-chloromuconate 6-semialdehyde
Other name(s): cnbC (gene name); 2-amino-5-chlorophenol:oxygen 1,6-oxidoreductase (decyclizing)
Systematic name: 2-amino-5-chlorophenol:oxygen 1,6-oxidoreductase (ring-opening)
Comments: The enzyme, a member of the nonheme-iron(II)-dependent dioxygenase family, is an extradiol-type dioxygenase that utilizes a non-heme ferrous iron to cleave the aromatic ring at the meta position (relative to the hydroxyl substituent). The enzyme from the bacterium Comamonas testosteroni CNB-1 also has the activity of EC, 2-aminophenol 1,6-dioxygenase.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, PDB
1.  Wu, J.F., Sun, C.W., Jiang, C.Y., Liu, Z.P. and Liu, S.J. A novel 2-aminophenol 1,6-dioxygenase involved in the degradation of p-chloronitrobenzene by Comamonas strain CNB-1: purification, properties, genetic cloning and expression in Escherichia coli. Arch. Microbiol. 183 (2005) 1–8. [DOI] [PMID: 15580337]
[EC created 2013]

Data © 2001–2024 IUBMB
Web site © 2005–2024 Andrew McDonald