EC Cystathionine γ-Lyase

EC Homocysteine Desulfhydrase

EC Methionine γ-Lyase


© IUBMB 2005

The mechanism shown is that of Brzovic, P., Holbrook, E.L., Greene, R.C. and Dunn, M.F. Reaction mechanism of Escherichia coli γ-synthase: direct evidence for a pyridoxamine derivative of vinylglyoxylate as a key intermediate in pyridoxal phosphate dependent γ-elimination and γ-replacement reactions. Biochemistry 29 (1990) 442-451. [PMID: 2405904], see also Inoue, H., Inagaki, K., Adachi, N., Tamura, T., Esaki, N., Soda, K. and Tanaka, H. Role of tyrosine 114 of L-methionine γ-lyase from Pseudomonas putida. Biosci. Biotechnol. Biochem. 64 (2000) 2336-2343. [PMID: 11193400]

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EC cystathionine γ-lyase
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EC methionine γ-lyase