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These early steps do not occur in mammals, which need pantothenic acid in their diet.
© IUBMB 2003
coenzyme A biosynthesis (late stages)
EC 188.8.131.52 2-dehydropantoate 2-reductase
EC 184.108.40.206 3-methyl-2-oxobutanoate hydroxymethyltransferase
EC 220.127.116.11 branched-chain-amino-acid transaminase
EC 18.104.22.168 aspartate 1-decarboxylase
EC 22.214.171.124 pantoateβ-alanine ligase (AMP forming)
EC 126.96.36.199 pantoateβ-alanine ligase (ADP forming)