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© IUBMB 2003
Note: The upper part of the diagram shows mammalian metabolism. The three enzymes shown at the bottom, EC 188.8.131.52, EC 184.108.40.206, and EC 220.127.116.11, are not known to occur in mammals.
EC 18.104.22.168 guanidinoacetate N-methyltransferase
EC 22.214.171.124 glycine amidinotransferase
EC 126.96.36.199 creatine kinase
EC 188.8.131.52 N-carbamoylsarcosine amidase
EC 184.108.40.206 N-methylhydantoinase (ATP-hydrolysing)
EC 220.127.116.11 creatinase
EC 18.104.22.168 creatinine deaminase