| EC |
1.14.13.43 |
| Accepted name: |
questin monooxygenase |
| Reaction: |
questin + NADPH + H+ + O2 = demethylsulochrin + NADP+ |
| Glossary: |
questin = 3,8-dihydroxy-1-methoxy-6-methylanthracene-9,10-dione
demethylsulochrin = 2-(2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxybenzoic acid |
| Other name(s): |
questin oxygenase |
| Systematic name: |
questin,NADPH:oxygen oxidoreductase (hydroxylating, anthraquinone-ring-opening) |
| Comments: |
The enzyme cleaves the anthraquinone ring of questin to form a benzophenone. Involved in the biosynthesis of the seco-anthraquinone (+)-geodin. |
| References: |
| 1. |
Fujii, I., Ebizuka, Y. and Sankawa, U. A novel anthraquinone ring cleavage enzyme from Aspergillus terreus. J. Biochem. (Tokyo) 103 (1988) 878–883. [PMID: 3182756] |
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| [EC 1.14.13.43 created 1992] |
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| EC |
2.1.1.283 |
| Accepted name: |
emodin O-methyltransferase |
| Reaction: |
S-adenosyl-L-methionine + emodin = S-adenosyl-L-homocysteine + questin |
| Glossary: |
emodin = 1,3,8-trihydroxy-6-methyl-9,10-anthraquinone
questin = 1,6-dihydroxy-8-methoxy-3-methyl-9,10-anthraquinone |
| Other name(s): |
EOMT |
| Systematic name: |
S-adenosyl-L-methionine:emodin 8-O-methyltransferase |
| Comments: |
The enzyme is involved in biosynthesis of the seco-anthraquinone (+)-geodin. |
| References: |
| 1. |
Chen, Z.G., Fujii, I., Ebizuka, Y. and Sankawa, U. Emodin O-methyltransferase from Aspergillus terreus. Arch. Microbiol. 158 (1992) 29–34. [PMID: 1444712] |
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| [EC 2.1.1.283 created 2013] |
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