| EC |
2.1.1.240 |
| Accepted name: |
trans-resveratrol di-O-methyltransferase |
| Reaction: |
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction)
(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4′,5-dihydroxy-trans-stilbene
(1b) S-adenosyl-L-methionine + 3-methoxy-4′,5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene |
| Glossary: |
3-methoxy-4′,5-dihydroxy-trans-stilbene = resveratrol monomethyl ether
pterostilbene = 3,5-dimethoxy-4′-hydroxy-trans-stilbene
trans-resveratrol = 3,4′,5-trihydroxy-trans-stilbene |
| Other name(s): |
ROMT; resveratrol O-methyltransferase; pterostilbene synthase |
| Systematic name: |
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase |
| Comments: |
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol. |
| References: |
| 1. |
Schmidlin, L., Poutaraud, A., Claudel, P., Mestre, P., Prado, E., Santos-Rosa, M., Wiedemann-Merdinoglu, S., Karst, F., Merdinoglu, D. and Hugueney, P. A stress-inducible resveratrol O-methyltransferase involved in the biosynthesis of pterostilbene in grapevine. Plant Physiol. 148 (2008) 1630–1639. [PMID: 18799660] |
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| [EC 2.1.1.240 created 2012] |
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