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Your query returned 3 entries. Printable version
EC | 1.14.11.36 | ||
Accepted name: | pentalenolactone F synthase | ||
Reaction: | pentalenolactone D + 2 2-oxoglutarate + 2 O2 = pentalenolactone F + 2 succinate + 2 CO2 + H2O (overall reaction) (1a) pentalenolactone D + 2-oxoglutarate + O2 = pentalenolactone E + succinate + CO2 + H2O (1b) pentalenolactone E + 2-oxoglutarate + O2 = pentalenolactone F + succinate + CO2 |
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For diagram of pentalenolactone biosynthesis, click here | |||
Glossary: | pentalenolactone D = (1S,4aR,6aS,9aR)-1,8,8-trimethyl-2-oxo-1,2,4,4a,6a,7,8,9-octahydropentaleno[1,6a-c]pyran-5-carboxylate pentalenolactone E = (4aR,6aS,9aR)-8,8-dimethyl-1-methylene-2-oxo-1,2,4,4a,6a,7,8,9-octahydropentaleno[1,6a-c]pyran-5-carboxylate pentalenolactone F = (1′R,4′aR,6′aS,9′aR)-8′,8′-dimethyl-2′-oxo-4′,4′a,6′a,8′,9′-hexahydrospiro[oxirane-2,1′-pentaleno[1,6a-c]pyran]-5′-carboxylic acid |
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Other name(s): | penD (gene name); pntD (gene name); ptlD (gene name) | ||
Systematic name: | pentalenolactone-D,2-oxoglutarate:oxygen oxidoreductase | ||
Comments: | Requires iron(II) and ascorbate. Isolated from the bacteria Streptomyces exfoliatus, Streptomyces arenae and Streptomyces avermitilis. Part of the pentalenolactone biosynthesis pathway. | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
References: |
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EC | 1.14.13.170 | ||
Accepted name: | pentalenolactone D synthase | ||
Reaction: | 1-deoxy-11-oxopentalenate + NADPH + H+ + O2 = pentalenolactone D + NADP+ + H2O | ||
For diagram of pentalenolactone biosynthesis, click here | |||
Glossary: | 1-deoxy-11-oxopentalenate = (1S,3aR,5aS)-1,7,7-trimethyl-2-oxo-1,2,3,3a,5a,6,7,8-octahydrocyclopenta[c]pentalene-4-carboxylate pentalenolactone D = (1S,4aR,6aS,9aR)-1,8,8-trimethyl-2-oxo-1,2,4,4a,6a,7,8,9-octahydropentaleno[1,6a-c]pyran-5-carboxylate |
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Other name(s): | penE (gene name); pntE (gene name) | ||
Systematic name: | 1-deoxy-11-oxopentalenate,NADH:oxygen oxidoreductase (pentalenolactone-D-forming) | ||
Comments: | A FAD-dependent oxygenase. Isolated from the bacteria Streptomyces exfoliatus and Streptomyces arenae. The ketone undergoes a biological Baeyer-Villiger reaction. Part of the pathway of pentalenolactone biosynthesis. | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
References: |
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EC | 1.14.13.171 | ||
Accepted name: | neopentalenolactone D synthase | ||
Reaction: | 1-deoxy-11-oxopentalenate + NADPH + H+ + O2 = neopentalenolactone D + NADP+ + H2O | ||
For diagram of pentalenolactone biosynthesis, click here | |||
Glossary: | 1-deoxy-11-oxopentalenate = (1S,3aR,5aS)-1,7,7-trimethyl-2-oxo-1,2,3,3a,5a,6,7,8-octahydrocyclopenta[c]pentalene-4-carboxylate neopentalenolactone D = (1S,4aR,6aS)-1,7,7-trimethyl-3-oxo-4,4a,6a,7,8,9-hexahydro-3H-pentaleno[6a,1-c]pyran-5-carboxylate |
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Other name(s): | ptlE (gene name) | ||
Systematic name: | 1-deoxy-11-oxopentalenate,NADH:oxygen oxidoreductase (neopentalenolactone-D-forming) | ||
Comments: | A FAD-dependent oxygenase. Isolated from the bacterium Streptomyces avermitilis. The ketone undergoes a biological Baeyer-Villiger reaction. | ||
Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
References: |
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