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Your query returned 4 entries. 
Printable version
| EC | 1.1.1.230 | ||
| Accepted name: | 3α-hydroxyglycyrrhetinate dehydrogenase | ||
| Reaction: | 3α-hydroxyglycyrrhetinate + NADP+ = 3-oxoglycyrrhetinate + NADPH + H+ | ||
| Systematic name: | 3α-hydroxyglycyrrhetinate:NADP+ 3-oxidoreductase | ||
| Comments: | Highly specific to 3α-hydroxy derivatives of glycyrrhetinate and its analogues. Not identical to EC 1.1.1.50 3α-hydroxysteroid dehydrogenase (Si-specific). | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 114308-07-5 | ||
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| EC | 1.14.13.173 | ||
| Transferred entry: | 11-oxo-β-amyrin 30-oxidase. Now EC 1.14.14.115, 11-oxo-β-amyrin 30-oxidase. | ||
| EC | 1.14.14.115 | ||
| Accepted name: | 11-oxo-β-amyrin 30-oxidase | ||
| Reaction: | 11-oxo-β-amyrin + 3 O2 + 3 [reduced NADPH—hemoprotein reductase] = glycyrrhetinate + 3 [oxidized NADPH—hemoprotein reductase] + 4 H2O (overall reaction) (1a) 11-oxo-β-amyrin + O2 + [reduced NADPH—hemoprotein reductase] = 30-hydroxy-11-oxo-β-amyrin + [oxidized NADPH—hemoprotein reductase] + H2O (1b) 30-hydroxy-11-oxo-β-amyrin + O2 + [reduced NADPH—hemoprotein reductase] = glycyrrhetaldehyde + [oxidized NADPH—hemoprotein reductase] + 2 H2O (1c) glycyrrhetaldehyde + O2 + [reduced NADPH—hemoprotein reductase] = glycyrrhetinate + [oxidized NADPH—hemoprotein reductase] + H2O |
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| For diagram of glycyrrhenate biosynthesis, click here | |||
| Other name(s): | CYP72A; CYP72A154; 11-oxo-β-amyrin 30-monooxygenase | ||
| Systematic name: | 11-oxo-β-amyrin,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase (30-hydroxylating) | ||
| Comments: | A cytochrome P-450 (heme-thiolate) protein. The enzyme from the plant Glycyrrhiza uralensis (licorice) is involved in the biosynthesis of the triterpenoid saponin glycyrrhizin. The enzyme from the plant Medicago truncatula can also hydroxylate β-amyrin. | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc | ||
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| EC | 3.2.1.128 | ||
| Accepted name: | glycyrrhizin hydrolase | ||
| Reaction: | glycyrrhizin + H2O = β-D-glucuronosyl-(1→2)-D-glucuronate + glycyrrhetinate | ||
| Glossary: | glycyrrhizin = glycyrrhizinate glycyrrhetinate = 3-β-glycyrrhetinate = 3β-hydroxy-11-oxoolean-12-en-30-oate |
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| Other name(s): | glycyrrhizinate β-glucuronidase; glycyrrhizin β-hydrolase; glycyrrhizinic acid hydrolase | ||
| Systematic name: | glycyrrhizinate glucuronosylhydrolase | ||
| Comments: | The enzyme from Aspergillus niger is specific for the hydrolysis of the triterpenoid glycoside glycyrrhizin from roots of Glycyrrhiza sp. | ||
| Links to other databases: | BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number: 102484-56-0 | ||
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