EC |
4.8.1.7 |
Accepted name: |
phenyl-N-(sulfonatooxy)methanimidothioate sulfolyase |
Reaction: |
phenyl-N-(sulfonatooxy)methanimidothioate = benzylthiocyanate + sulfate |
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For diagram of glucotropeolin biosynthesis and catabolism, click here |
Glossary: |
glucotropaeolin = 1-S-[(1Z)-2-phenyl-N-(sulfonatooxy)ethanimidoyl]-1-thio-β-D-glucopyranose |
Other name(s): |
TFP (gene name) (ambiguous); thiocyanate-forming protein (ambiguous) |
Systematic name: |
phenyl-N-(sulfonatooxy)methanimidothioate sulfate-lyase (benzylthiocyanate-forming) |
Comments: |
The enzyme, characterized from the plant Lepidium sativum, is involved in the breakdown of the glucosinolate glucotropaeolin. Depending on the substrate, it can also form simple nitrile- and epithionitrile-containing products. cf. EC 4.8.1.5, thiohydroximate-O-sulfate sulfate/sulfur-lyase (nitrile-forming), and EC 4.8.1.6, N-(sulfonatooxy)alkenimidothioic acid sulfate-lyase (epithionitrile-forming). |
Links to other databases: |
BRENDA, EXPASY, KEGG, MetaCyc |
References: |
1. |
Burow, M., Bergner, A., Gershenzon, J. and Wittstock, U. Glucosinolate hydrolysis in Lepidium sativum - identification of the thiocyanate-forming protein. Plant Mol. Biol. 63 (2007) 49–61. [DOI] [PMID: 17139450] |
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[EC 4.8.1.7 created 2022] |
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