EC	1.14.14.66
Accepted name:	marmesin synthase
Reaction:	demethylsuberosin + [reduced NADPH—hemoprotein reductase] + O2 = (+)-marmesin + [oxidized NADPH—hemoprotein reductase] + H2O
Glossary:	demethylsuberosin = 7-hydroxy-6-prenyl-1-benzopyran-2-one (+)-marmesin = (S)-2-(2-hydroxypropan-2-yl)-2,3-dihydro-7H-furo[3,2-g]chromen-7-one
Systematic name:	demethylsuberosin,[reduced NADPH—hemoprotein reductase]:oxygen oxidoreductase
Comments:	A P-450 monoxygenase involved in psoralen biosynthesis, see EC 1.14.13.102, psoralen synthase.
References:	1.  Hamerski, D. and Matern, U. Elicitor-induced biosynthesis of psoralens in Ammi majus L. suspension cultures. Microsomal conversion of demethylsuberosin into (+)marmesin and psoralen. Eur. J. Biochem. 171 (1988) 369–375. [PMID: 2828055]
[EC 1.14.14.66 created 2018]
EC	2.5.1.139
Accepted name:	umbelliferone 6-dimethylallyltransferase
Reaction:	prenyl diphosphate + umbelliferone = diphosphate + demethylsuberosin
Glossary:	demethylsuberosin = 7-hydroxy-6-prenyl-1-benzopyran-2-one osthenol = 7-hydroxy-8-prenyl-1-benzopyran-2-one
Other name(s):	PcPT; dimethylallyl-diphosphate:umbelliferone 6-dimethylallyltransferase
Systematic name:	prenyl-diphosphate:umbelliferone 6-prenyltransferase
Comments:	The enzyme from parsley (Petroselinum crispum) is specific for umbelliferone and prenyl diphosphate. A minor product is osthenol, which is produced by transfer of the prenyl group to C-8 of umbelliferone.
References:	1.  Hamerski, D., Schmitt, D. and Matern, U. Induction of two prenyltransferases for the accumulation of coumarin phytoalexins in elicitor-treated Ammi majus cell suspension cultures. Phytochemistry 29 (1990) 1131–1135. [PMID: 1366425] 2.  Karamat, F., Olry, A., Munakata, R., Koeduka, T., Sugiyama, A., Paris, C., Hehn, A., Bourgaud, F. and Yazaki, K. A coumarin-specific prenyltransferase catalyzes the crucial biosynthetic reaction for furanocoumarin formation in parsley. Plant J. 77 (2014) 627–638. [PMID: 24354545]
[EC 2.5.1.139 created 2017]